Hi Simon. I'm not particularly worried about these things happening.
It won't cause moisture to build up in the insulation or roof void. For that to happen you need 2 things: A defective or non existent vapour barrier on the warm side of the insulation, and a vapour barrier/total lack of ventilation on the cold side. I have only ever come across such a situation once, a barn conversion where the builder had used DPM as the roofing underfelt, and left no ventilation at all. The small loft above the vaulted ceiling was damp due to the condensation that would form up there. Any sort of ventilation, or breathable membrane, as should be in place such a roof structure, will prevent that from happening.
It will, however create a cold spot on the ceiling, and so there is a small possibility of mould forming there. I think the risk is low - it tends to happen in moist areas of poorly ventilated houses, which this isn't. A solution is to use insulation coverable downlights, and backfill any void created with rockwool, eliminating the cold spot.